GABRB3
Reactivity: Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/8000. Immunohistochemistry on paraffin sections: Human Cortex shows patchy staining near orat the neuronal cell membrane. Recommended concentration: 2-4 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
GABRB3
(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
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Background
GABA A Receptor beta 3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. The GABAA receptor complex is the molecular target of the benzodiazepine class of tranquilizer drugs, and hence it is also often referred to as the 'benzodiazepine receptor'. The GABAA receptor complex also appears to have distinct binding sites for a variety of other pharmaco-active compounds.Synonyms: GABA A receptor subunit beta-3, GABRB-3, Gamma-aminobutyric acid receptor subunit beta-3