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GABRB3 Products

(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

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This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2010].

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Featured GABRB3 Categories

GABRB3 Antibodies

High quality antibodies with extensive validation data.

GABRB3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRB3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7153497
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN1742465
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN6254101
Quantity 100 μL
Datasheet Datasheet

Recommended GABRB3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354661
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3080563
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3120836
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GABRB3 products

Pandya, Palpagama, Turner, Waldvogel, Faull, Kwakowsky: "Sex- and age-related changes in GABA signaling components in the human cortex." in: Biology of sex differences, Vol. 10, Issue 1, pp. 5, (2019) (PubMed).

Palpagama, Sagniez, Kim, Waldvogel, Faull, Kwakowsky: "GABAA Receptors Are Well Preserved in the Hippocampus of Aged Mice." in: eNeuro, Vol. 6, Issue 4, (2019) (PubMed).

Li, Li, Jia, Cao, Wang, Wang, Luo, Zhou, Liu, Mao: "Sodium Valproate Ameliorates Neuronal Apoptosis in a Kainic Acid Model of Epilepsy via Enhancing PKC-Dependent GABAAR γ2 Serine 327 Phosphorylation." in: Neurochemical research, Vol. 43, Issue 12, pp. 2343-2352, (2018) (PubMed).

Brewer, Liu, Buhler, Shirachi, Quock: "Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen." in: Brain research, Vol. 1699, pp. 107-116, (2018) (PubMed).

Bocker, Heinrich, Liebmann, Hennings, Seemann, Gerth, Jakovcevski, Preobraschenski, Kessels, Westermann, Isbrandt, Jahn, Qualmann, Hübner: "The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release." in: Cerebral cortex (New York, N.Y. : 1991), (2018) (PubMed).

Lu, Liu, Jiang, Pan, Ho, Ho: "Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain." in: Neural plasticity, Vol. 2017, pp. 5715816, (2017) (PubMed).

Bohnsack, Carlson, Morrow: "Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons." in: Neuropharmacology, Vol. 105, pp. 124-32, (2016) (PubMed).

Babateen, Jin, Bhandage, Korol, Westermark, Forsberg Nilsson, Uhrbom, Smits, Birnir: "Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma." in: European journal of pharmacology, Vol. 748, pp. 101-7, (2015) (PubMed).

He, Duguid, Clark, Panzanelli, Patel, Thomas, Fritschy, Smart: "Interneuron- and GABAA receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells." in: Nature communications, Vol. 6, pp. 7364, (2015) (PubMed).

Nunes, Kuner: "Disinhibition of olfactory bulb granule cells accelerates odour discrimination in mice." in: Nature communications, Vol. 6, pp. 8950, (2015) (PubMed).

Synonyms and alternative names related to GABRB3

gamma-aminobutyric acid type A receptor beta3 subunit (GABRB3), gamma-aminobutyric acid (GABA) A receptor, beta 3 (gabrb3), gamma-aminobutyric acid type A receptor beta 3 subunit (Gabrb3), gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 (Gabrb3), A230092K12Rik, AW049585, beta3, Cp1, eca5, ECA5, Gabrb-3, GABRB3, LOC100230475

Protein level used designations for GABRB3

  • gamma-aminobutyric acid (GABA) A receptor, beta 3
  • gamma-aminobutyric acid receptor subunit beta-3
  • gamma-aminobutyric acid A receptor beta 3
  • gamma-aminobutyric acid receptor subunit beta-3-like
  • GABA-alpha receptor beta-2 subunit
  • GABAA receptor beta-3 subunit
  • GABA(A) receptor subunit beta-3
  • Gamma-aminobutyric acid receptor beta 3
  • gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3
  • gamma-aminobutyric acid receptor, subunit beta 3
  • testis gamma-aminobutyric acid receptor subunit beta 3
  • GABA-A receptor beta-3 subunit
  • cleft palate 1
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