anti-FOXA1 antibody (Forkhead Box A1) (N-Term)

Details for Product anti-FOXA1 Antibody No. ABIN501688, Supplier: Login to see New
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Antigen
Synonyms
FoxA4a, XFD-1, fkh1, foxa1, pintallavis, xfkh1, xkfh-1, HNF3-alpha, HNF3alpha, Hnf3a, fkh2, tFoxA1, tcf3a, xfkh2, fkh, FOXA1, Ci-fkh, foxa3, Foxa1, fkd7, forkhead-7, hnf3a, HNF3A, TCF3A, HNF-3a, Hnf-3 ... show more
FoxA4a, XFD-1, fkh1, foxa1, pintallavis, xfkh1, xkfh-1, HNF3-alpha, HNF3alpha, Hnf3a, fkh2, tFoxA1, tcf3a, xfkh2, fkh, FOXA1, Ci-fkh, foxa3, Foxa1, fkd7, forkhead-7, hnf3a, HNF3A, TCF3A, HNF-3a, Hnf-3a, Tcf-3a, Tcf3a show less
Epitope
N-Term
(38), (19), (16), (15), (13), (7), (6), (6), (5), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(154), (32), (24), (6), (5), (5), (2), (1), (1), (1)
Host
Rabbit
(77), (55), (22)
Clonality
Polyclonal
Conjugate
This FOXA1 antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(116), (73), (54), (34), (26), (11), (10), (9), (7), (7), (6), (3), (3), (2), (1), (1)
Pubmed 2 references available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human FOXA1
Sequence LGTVKMEGHE TSDWNSYYAD TQEAYSSVPV SNMNSGLGSM NSMNTYMTMN
Predicted Reactivity Human : 100 %, Bovine : 90 %, Dog : 90 %, Pig : 90 %, Mouse : 80 %, Rat : 80 %, African clawed frog : 80 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against FOXA1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FOXA1 (FOXA1 Antibody Abstract)
Background FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
Molecular Weight 49 kDa
Gene ID 3169
NCBI Accession NP_004487, NM_004496
UniProt P55317
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 472 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-FOXA1 antibody (Forkhead Box A1) (N-Term) (ABIN501688) WB Suggested Anti-FOXA1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-FOXA1 antibody (Forkhead Box A1) (N-Term) (ABIN501688) Sample Type: 1. Control (20ug)
2. shRNA1-FOXA1 H9 hES cells (20ug)
3. sh...
Product cited in: Menga, Infantino, Iacobazzi et al.: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, 2013 (PubMed).

Background publications Lupien, Eeckhoute, Meyer et al.: "FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription." in: Cell, Vol. 132, Issue 6, pp. 958-70, 2008 (PubMed).

Catalog No. ABIN501688
$289.00
Plus shipping costs $45.00

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