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AP3D1 antibody (AA 400-680)
AP3D1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AP3D1 Antibody
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Target
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AP3D1
(Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))
Binding Specificity
All epitopes for AP3D1 antibodies
AA 400-680
Reactivity
All reactivities for AP3D1 antibodies
Human
Host
All hosts for AP3D1 antibodies
Rabbit
Clonality
All clonalities for AP3D1 antibodies
Polyclonal
Conjugate
All conjugates for AP3D1 antibodies
This AP3D1 antibody is un-conjugated
Application
All applications for AP3D1 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant AP3 Delta protein (amino acids 400-680) was used as the immunogen for this antibody.
Isotype
IgG
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Application Details
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Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for AP3D1
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Target
AP3D1
(Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))
Alternative Name
AP3 Delta (AP3D1 Products )
Synonyms
wu:fj51g01 antibody, si:ch211-129c21.6 antibody, ADTD antibody, hBLVR antibody, AA407035 antibody, Ap3d antibody, Bolvr antibody, mBLVR1 antibody, mh antibody, mocha antibody, BLVR antibody, adaptor-related protein complex 3, delta 1 subunit antibody, AP-3 complex subunit delta-1 antibody, adaptor related protein complex 3 delta 1 subunit antibody, ap3d1 antibody, EDI_172030 antibody, EHI_158840 antibody, Tsp_04773 antibody, AP3D1 antibody, Ap3d1 antibody
Background
AP3D1 (AP-3 complex subunit delta-1) encodes the delta 1 subunit of an adaptor protein regulating intracellular vesicle-mediated transport (19631730). Lack of expression of functional AP-3, leads to a deficiency in vesicle transport and storage, which affects neurotransmitter vesicle turnover and release in the central nervous system (19032734). The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and directly involved in trafficking to lysosomes. It is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.
Molecular Weight
122 kDa
Gene ID
8943
UniProt
O14617
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