NTRK3 antibody (C-Term)
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- Target See all NTRK3 Antibodies
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Pig, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NTRK3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ERPRVCPKEV YDVMLGCWQR EPQQRLNIKE IYKILHALGK ATPIYLDILG
- Predicted Reactivity
- Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against NTRK3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK3
- Top Product
- Discover our top product NTRK3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 825 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Alternative Name
- NTRK3 (NTRK3 Products)
- Synonyms
- TRKC antibody, gp145(trkC) antibody, trkC antibody, AW125844 antibody, Ntrk3_tv3 antibody, TrkC antibody, neurotrophic receptor tyrosine kinase 3 antibody, neurotrophic tyrosine kinase, receptor, type 3 antibody, NTRK3 antibody, Ntrk3 antibody
- Background
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NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Alias Symbols: TRKC, gp145(trkC)
Protein Interaction Partner: TNK2, IRAK3, HSP90AA1, APP, SHC2, KIDINS220, DOK5, RASGRF1, MAPK3, DYNLL1, SQSTM1, SHC1, NGFRAP1, IRAK1, HTR2A, MAPK1, PTPN1, PLCG1, JUN, NTF3, NGFR, FRS2,
Protein Size: 825 - Molecular Weight
- 89 kDa
- Gene ID
- 4916
- NCBI Accession
- NM_002530, NP_002521
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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