Nibrin antibody (AA 350-400)
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- Target See all Nibrin (NBN) Antibodies
- Nibrin (NBN)
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Binding Specificity
- AA 350-400
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Nibrin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse (Murine)
- Purification
- affinity purified
- Immunogen
- Synthetic peptide made to an internal portion of the mouse protein (within AA 350-400). [Swiss-Prot# Q9R207].
- Isotype
- IgG
- Top Product
- Discover our top product NBN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- -20 °C
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- Target
- Nibrin (NBN)
- Alternative Name
- p95/NBS1 (NBN Products)
- Synonyms
- NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody
- Background
- The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
- UniProt
- Q9R207
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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