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MYL12A antibody (N-Term)
MYL12A
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MYL12A Antibody
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Target
See all MYL12A Antibodies
MYL12A
(Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))
Binding Specificity
All epitopes for MYL12A antibodies
N-Term
Reactivity
All reactivities for MYL12A antibodies
Human
Host
All hosts for MYL12A antibodies
Rabbit
Clonality
All clonalities for MYL12A antibodies
Polyclonal
Conjugate
All conjugates for MYL12A antibodies
This MYL12A antibody is un-conjugated
Application
All applications for MYL12A antibodies
Western Blotting (WB)
Sequence
MSSKRTKTKT KKRPQRATSN VFAMFDQSQI QEFKEAFNMI DQNRDGFIDK
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MYL12A
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MYL12A
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Target
MYL12A
(Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))
Alternative Name
MYL12A (MYL12A Products )
Synonyms
MLCB antibody, MRCL3 antibody, MRLC3 antibody, MYL2B antibody, RGD1309537 antibody, Rlc-a antibody, myosin light chain 12A antibody, MYL12A antibody, Myl12a antibody
Background
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. Alias Symbols: MLCB, MRCL3, MRLC3, MYL2B, MLC-2B, HEL-S-24 Protein Size: 171
Gene ID
10627
NCBI Accession
NM_001303047 , NP_001289976
UniProt
P19105
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