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MYL12A antibody (pSer18)
MYL12A
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MYL12A Antibody
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Target
See all MYL12A Antibodies
MYL12A
(Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))
Binding Specificity
All epitopes for MYL12A antibodies
pSer18
Reactivity
All reactivities for MYL12A antibodies
Human
Host
All hosts for MYL12A antibodies
Rabbit
Clonality
All clonalities for MYL12A antibodies
Polyclonal
Conjugate
All conjugates for MYL12A antibodies
This MYL12A antibody is un-conjugated
Application
All applications for MYL12A antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Cross-Reactivity
Human, Rat
Characteristics
Phosphorylated Antibodies
Immunogen
A phospho specific peptide corresponding to residues surrounding S18 of human MYL12A
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:100
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-MYL12A antibody (ABIN3020385)
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Niu, Pi, Baral, Xia, He, Li, Jin, Li, Wang, Mao, Hu : "P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis. " in: Arteriosclerosis, thrombosis, and vascular biology , Vol. 37 , Issue 3 , pp. 515-524 , (2017 ) (PubMed ).
Target Details for MYL12A
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Target
MYL12A
(Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))
Alternative Name
MYL12A (MYL12A Products )
Synonyms
MLCB antibody, MRCL3 antibody, MRLC3 antibody, MYL2B antibody, RGD1309537 antibody, Rlc-a antibody, myosin light chain 12A antibody, MYL12A antibody, Myl12a antibody
Background
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.,MYL12A,HEL-S-24,MLC-2B,MLCB,MRCL3,MRLC3,MYL2B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,Protein phosphorylation,MYL12A
Molecular Weight
19 kDa
Gene ID
10627
UniProt
P19105
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