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Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) antibody (PE)

Details for Product No. ABIN610121, Supplier: Log in to see
Antigen
  • LOC100219853
  • CD49D
  • IA4
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
  • integrin alpha 4
  • integrin, alpha 4
  • LOC100219853
  • Itga4
  • ITGA4
Reactivity
Human
259
214
73
15
10
10
9
9
8
7
7
5
4
4
3
2
2
2
2
2
1
1
Host
Mouse
180
173
66
Clonality (Clone)
Monoclonal ()
Conjugate
PE
66
56
30
8
8
6
4
4
3
2
2
2
2
2
2
2
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (IHC)
333
109
88
71
48
30
30
26
21
11
6
4
4
3
3
3
2
2
2
2
2
1
Options
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Immunogen Human peripheral myeloma cells.

Type of Immunogen: Cells
Clone BU49
Isotype IgG1
Specificity CD49d molecule of about 145 kd.
Purification Gel filtration
Alternative Name ITGA4 / VLA-4 / CD49d (ITGA4 Antibody Abstract)
Background Name/Gene ID: ITGA4
Family: Integrin

Synonyms: ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen
Gene ID 3676
UniProt P13612
Application Notes Approved: Flo, Func, IHC

Usage: Function: Blocks VLA-4 binding to VCAM-1. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Product is photosensitive and should be protected from light.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
Product cited in: Aplin, Stewart, Assoian, Juliano: "Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1." in: The Journal of cell biology, Vol. 153, Issue 2, pp. 273-82, 2001 (PubMed).

Short, Boyer, Juliano: "Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 12970-7, 2000 (PubMed).