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CTLA4 antibody (Biotin)

CTLA4 Reactivity: Human FACS, ELISA, Func Host: Mouse Monoclonal ANC152-2-8H5 Biotin
Catalog No. ABIN610401
  • Target See all CTLA4 Antibodies
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reactivity
    • 88
    • 57
    • 35
    • 5
    • 4
    Human
    Host
    • 59
    • 44
    • 13
    • 10
    • 1
    • 1
    Mouse
    Clonality
    • 71
    • 54
    • 2
    Monoclonal
    Conjugate
    • 59
    • 14
    • 13
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTLA4 antibody is conjugated to Biotin
    Application
    • 77
    • 63
    • 50
    • 33
    • 17
    • 14
    • 13
    • 13
    • 9
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Flow Cytometry (FACS), ELISA, Functional Studies (Func)
    Specificity
    CTLA-4 expressed on activated T cells.
    Purification
    Protein A purified
    Immunogen
    Stimulated human PBL’,s and human CD152 Ig fusion protein.

    Type of Immunogen: Fusion protein
    Clone
    ANC152-2-8H5
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • Application Notes
    Approved: ELISA, Flo, Func

    Usage: Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Alternative Name
    CTLA4 / CD152 (CTLA4 Products)
    Synonyms
    CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
    Background
    Name/Gene ID: CTLA4

    Synonyms: CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform
    Gene ID
    1493
    UniProt
    P16410
    Pathways
    Cancer Immune Checkpoints
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