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PDE8A antibody (phosphodiesterase 8A) (C-Term)

Details for Product anti-PDE8A Antibody No. ABIN611116, Supplier: Log in to see
Antigen
  • AI551852
  • HsT19550
  • Pde8
  • Pde8a
  • PDE8A
  • RNPDE8A
Epitope
C-Term
29
19
10
10
9
7
3
2
2
1
1
1
1
1
Reactivity
Human
72
11
11
9
2
2
2
2
1
1
Host
Rabbit
64
8
Clonality
Polyclonal
Conjugate
This PDE8A antibody is un-conjugated
7
4
4
4
4
4
Application
Western Blotting (WB)
45
38
38
14
10
8
8
6
1
Supplier
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Immunogen Synthetic peptide from C-terminus of human PDE8A (NP_002596.1, O60658).
Specificity Human PDE8A
Predicted Reactivity Percent identity by BLAST analysis: Human, Dog, Bovine, Rabbit, Horse, Guinea pig (100%) Mouse, Rat, Chicken, Zebrafish (92%).
Purification Immunoaffinity Chromatography
Alternative Name PDE8A (PDE8A Antibody Abstract)
Background Standard Gene Symbol: PDE8A, Gene Family: Phosphodiesterase, Gene Subfamily: PDE - cAMP-specific, high affinity, Synonyms: PDE8A, Phosphodiesterase 8A, HsT19550
Gene ID 5151
UniProt O60658
Research Area Signaling, Enzymes, Metabolism
Application Notes WB (0.2 - 1 µg/mL)
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Buffer Lyophilized from PBS with 2% sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.
Supplier Images
 image for anti-PDE8A antibody (phosphodiesterase 8A) (C-Term) (ABIN611116) anti-phosphodiesterase 8A (PDE8A) (C-Term) antibody
Product cited in: Shahan, Sorenson, Simpson, Kefalides, Lewis: "Tyrosine kinase activation in response to fungal spores is primarily dependent on endogenous reactive oxygen production in macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10175-81, 2000 (PubMed).

Yang, Malek, Desiderio: "An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20832-40, 1995 (PubMed).

Aoki, Isselbacher, Pillai: "Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 22, pp. 10606-9, 1994 (PubMed).

Vetrie, Vorechovský, Sideras, Holland, Davies, Flinter, Hammarström, Kinnon, Levinsky, Bobrow: "The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases." in: Nature, Vol. 361, Issue 6409, pp. 226-33, 1993 (PubMed).