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Aurora Kinase C antibody (N-Term)
AURKC
Reactivity: Human
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-Aurora Kinase C Antibody
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Target
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Aurora Kinase C (AURKC)
Binding Specificity
All epitopes for Aurora Kinase C antibodies
N-Term
Reactivity
All reactivities for Aurora Kinase C antibodies
Human
Host
All hosts for Aurora Kinase C antibodies
Goat
Clonality
All clonalities for Aurora Kinase C antibodies
Polyclonal
Conjugate
All conjugates for Aurora Kinase C antibodies
This Aurora Kinase C antibody is un-conjugated
Application
All applications for Aurora Kinase C antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
PRAVVQLGKA QP-C
Specificity
This antibody is expected to recognize isoform 1 (NP_001015878.1) only.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence from the N Terminus of the protein sequence according to NP_001015878.1. Genename: AURKC
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Aurora Kinase C
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Target
Aurora Kinase C (AURKC)
Alternative Name
Aurora Kinase C (AURKC Products )
Synonyms
AURKC antibody, AIE2 antibody, AIK3 antibody, ARK3 antibody, AurC antibody, SPGF5 antibody, STK13 antibody, aurora-C antibody, AIE1 antibody, ARK-3 antibody, IAK3 antibody, Stk13 antibody, aurora kinase C antibody, AURKC antibody, Aurkc antibody
Background
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.Synonyms: AIE2, AIK3, AURKC, Aurora-C, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 2, STK13, Serine/threonine-protein kinase 13
Gene ID
6795
NCBI Accession
NP_001015878
UniProt
Q9UQB9
Pathways
Cell Division Cycle , Maintenance of Protein Location
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