anti-IGFBP4 antibody (Insulin-Like Growth Factor Binding Protein 4) (AA 96-124)

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Antigen
Synonyms IGFBP4, igfbp4, BP-4, HT29-IGFBP, IBP4, IGFBP-4, AI875747, Deb2, IGF-BP4, IBP-4
Alternatives
Epitope
AA 96-124, Center
(21), (16), (15), (15), (14), (13), (9), (3), (3), (2), (2), (2), (2), (1), (1)
Reactivity
Human, Mouse (Murine)
(114), (23), (19), (8), (7), (3), (3), (3), (2), (1), (1), (1)
Host
Rabbit
(86), (35), (18)
Clonality (Clone)
Polyclonal ()
Conjugate
This IGFBP4 antibody is un-conjugated
(10), (10), (5), (5), (5), (5), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(106), (98), (28), (18), (15), (13), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Pubmed 1 reference available
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Quantity 400 μL
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Immunogen This IGFBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 AA from the Central region of human IGFBP4.
Clone RB20480
Isotype Ig
Specificity This IGFBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human IGFBP4.
Predicted Reactivity Cow (Bovine),Pig (Porcine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IGFBP4 (IGFBP4 Antibody Abstract)
Background This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Synonyms: Insulin-like growth factor-binding protein 4,IGFBP4,IBP4
Molecular Weight 27934 DA
Gene ID 3487
NCBI Accession NP_001543
UniProt P22692
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Pathways WNT Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-IGFBP4 antibody (Insulin-Like Growth Factor Binding Protein 4) (AA 96-124) (ABIN652262) IGFBP4 Antibody (Center) (ABIN652262) western blot analysis in mouse lung tissue lysa...
Immunohistochemistry (IHC) image for anti-IGFBP4 antibody (Insulin-Like Growth Factor Binding Protein 4) (AA 96-124) (ABIN652262) IGFBP4 antibody (Center) (ABIN652262) immunohistochemistry analysis in formalin fixed...
Background publications Canzian, Cox, Setiawan et al.: "Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3873-84, 2010 (PubMed).

Catalog No. ABIN652262
$324.50
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Plus shipping costs $45.00

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