You are viewing an incomplete version of our website. Please click to reload the website as full version.

Leucyl/cystinyl Aminopeptidase (LNPEP) (AA 23-52), (N-Term) antibody

Details for Product No. ABIN654230, Supplier: Log in to see
Antigen
  • fb73h12
  • wu:fb73h12
  • zgc:66103
  • 2010309L07Rik
  • 4732490P18Rik
  • CAP
  • IRAP
  • PLAP
  • gp160
  • vp165
  • P-LAP
  • Vp165
  • LNPEP
Epitope
AA 23-52, N-Term
15
14
6
2
1
1
1
1
Reactivity
Human
35
7
3
Host
Rabbit
35
2
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
26
15
14
6
6
4
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This LNPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 AA from the N-terminal region of human LNPEP.
Clone RB27638
Isotype Ig
Specificity This LNPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human LNPEP.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LNPEP (LNPEP Antibody Abstract)
Background This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Synonyms: Leucyl-cystinyl aminopeptidase,LNPEP,OTASE
Molecular Weight 117349 DA
Gene ID 4012
NCBI Accession NP_787116, NP_005566
UniProt Q9UIQ6
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Metabolism
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Leucyl/cystinyl Aminopeptidase (LNPEP) (AA 23-52), (N-Term) antibody (ABIN654230) LNPEP Antibody (N-Term) western blot analysis in HL-60 cell line lysates (35ug/lane)...
Immunohistochemistry (IHC) image for anti-Leucyl/cystinyl Aminopeptidase (LNPEP) (AA 23-52), (N-Term) antibody (ABIN654230) LNPEP antibody (N-Term) immunohistochemistry analysis in formalin fixed and paraffin...
Flow Cytometry (FACS) image for anti-Leucyl/cystinyl Aminopeptidase (LNPEP) (AA 23-52), (N-Term) antibody (ABIN654230) LNPEP Antibody (N-Term) flow cytometric analysis of HL-60 cells (right histogram) co...
Background publications Georgiadou, Hearn, Evnouchidou et al.: "Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1584-92, 2010 (PubMed).

Saveanu, Carroll, Weimershaus et al.: "IRAP identifies an endosomal compartment required for MHC class I cross-presentation." in: Science (New York, N.Y.), Vol. 325, Issue 5937, pp. 213-7, 2009 (PubMed).