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MAP3K11 antibody
MAP3K11
Reactivity: Human
WB
Host: Mouse
Monoclonal
230CT5-3-1
unconjugated
Product Details anti-MAP3K11 Antibody
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Target
See all MAP3K11 Antibodies
MAP3K11
(Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
Reactivity
All reactivities for MAP3K11 antibodies
Human
Host
All hosts for MAP3K11 antibodies
Mouse
Clonality
All clonalities for MAP3K11 antibodies
Monoclonal
Conjugate
All conjugates for MAP3K11 antibodies
This MAP3K11 antibody is un-conjugated
Application
All applications for MAP3K11 antibodies
Western Blotting (WB)
Purification
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Immunogen
This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein.
Clone
230CT5-3-1
Isotype
IgM kappa
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Alternatives
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Application Details
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Application Notes
WB: 1:100~500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
MAP3K11 Antibody (ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Target Details for MAP3K11
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Target
MAP3K11
(Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
Alternative Name
MAP3K11 (MAP3K11 Products )
Synonyms
MEKK11 antibody, MLK-3 antibody, MLK3 antibody, PTK1 antibody, SPRK antibody, 2610017K16Rik antibody, Mlk3 antibody, Mlk-3 antibody, RHOE antibody, mitogen-activated protein kinase kinase kinase 11 antibody, MAP3K11 antibody, Map3k11 antibody
Background
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Molecular Weight
92688
Gene ID
4296
NCBI Accession
NP_002410
UniProt
Q16584
Pathways
MAPK Signaling , Interferon-gamma Pathway
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