FADD Protein (AA 1-208) (GST tag)
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- Target See all FADD Proteins
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-208
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FADD protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- FADD,1-208aa, Human GST-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product FADD Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in phosphate-buffered Saline (PBS), 20% Glycerol
- Storage
- 4 °C
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- Target
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Alternative Name
- FADD (FADD Products)
- Synonyms
- MORT1 Protein, Mort1/FADD Protein, Mort1 Protein, TNFRSF6 Protein, adaptor Protein, fadd Protein, mort1 Protein, xfadd Protein, Fas associated via death domain Protein, Fas (TNFRSF6)-associated via death domain Protein, Fas associated via death domain S homeolog Protein, Fas (tnfrsf6)-associated via death domain Protein, FADD Protein, Fadd Protein, fadd.S Protein, fadd Protein
- Background
- FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules. Recombinant human FADD, fused to GST-tag, was expressed in E.coli and purified by conventional chromatography techniques. Synonyms: GIG3, MORT1, MGC8528, Fas-associated via death domain, FADD, Fas-associated via death domain FADD protein, Fas TNFRSF6 associated via death domain, Fas (TNFRSF6) associated via death domain, Fas associated via death domain, Fas associating protein, Fas associating death domain containing protein, Fas associating protein with death domain GIG 3, Growth inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity, MORT 1. NCBI no.: NP_003815
- Molecular Weight
- 49kDa (434aa), confirmed by MALDI-TOF.
- Pathways
- Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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