HES1 antibody (AA 41-150) (FITC)
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- Target See all HES1 Antibodies
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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Binding Specificity
- AA 41-150
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HES1 antibody is conjugated to FITC
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HES1
- Isotype
- IgG
- Top Product
- Discover our top product HES1 Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- Alternative Name
- HES1 (HES1 Products)
- Synonyms
- HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody
- Background
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Synonyms: HHL, HRY, HES-1, bHLHb39, Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, HES1, HL
Background: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
- Gene ID
- 3280
- UniProt
- Q14469
- Pathways
- DNA Damage Repair
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