GADD45A antibody (Growth Arrest and DNA-Damage-Inducible, alpha) (AA 100-150)

Details for Product anti-GADD45A Antibody No. ABIN685432, Supplier: Log in to see
Antigen
  • MGC53491
  • zgc:91795
  • gadd45a
  • GADD45A
  • ddit1
  • gadd45
  • GADD45
  • AA545191
  • Ddit1
  • DDIT1
  • Gadd45
  • growth arrest and DNA-damage-inducible, alpha
  • growth arrest and DNA-damage-inducible, alpha, b
  • growth arrest and DNA damage-inducible protein 45
  • growth arrest and DNA-damage-inducible 45 alpha
  • gadd45a
  • gadd45ab
  • GADD45A
  • GADD45
  • Gadd45a
Alternatives
anti-Human GADD45A antibody for Enzyme Immunoassay
Epitope
AA 100-150
15
14
11
5
4
4
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
82
34
33
4
3
2
2
2
2
1
Host
Rabbit
69
15
Clonality
Polyclonal
Conjugate
This GADD45A antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
65
20
14
12
6
4
3
3
3
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide derived from human GADD45
Isotype IgG
Purification Purified by Protein A.
Alternative Name Gadd45 (GADD45A Antibody Abstract)
Background

In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

Subcellular location: Nucleus

Synonyms: DDIT1, GADD45, Growth arrest and DNA damage-inducible protein GADD45 alpha, DNA damage-inducible transcript 1 protein, DDIT-1, GADD45A

Gene ID 1647
UniProt P24522
Pathways p53 Signaling, Cell Division Cycle
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 100-150) antibody (ABIN685432) Formalin-fixed and paraffin embedded rat heart labeled with Anti-GADD45 Polyclonal An...
SDS-PAGE (SDS) image for anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 100-150) antibody (ABIN685432) L1 rat brain lysates L2 rat kidney lysates probed with Anti IL-2R gamma/CD132 Polyclo...
Immunohistochemistry (IHC) image for anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 100-150) antibody (ABIN685432) Formalin-fixed and paraffin embedded rat brain labeled with Anti-GADD45 Polyclonal An...
Product cited in: Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, 2014 (PubMed).

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