PDX1 antibody (N-Term)
-
- Target See all PDX1 Antibodies
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig, Guinea Pig
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PDX1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- LYMGRQPPPP PPPQFTSSLG SLEQGSPPDI SPYEVPPLAS DDPAGAHLHH
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Pdx1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PDX1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 284 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Alternative Name
- Pdx1 (PDX1 Products)
- Synonyms
- GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
- Background
-
Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
Alias Symbols: IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
Protein Interaction Partner: Pcif1, Meis1, Hdac1, Hdac2, Ins1, Iapp, Spop, Pax4,
Protein Size: 284 - Molecular Weight
- 31 kDa
- Gene ID
- 18609
- NCBI Accession
- NM_008814, NP_032840
- UniProt
- P52946
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
-