IKK alpha antibody

Catalog No. ABIN865524

The Mouse Monoclonal anti-IKK alpha antibody (Clone 3G12H9) (ABIN865524) specifically detects IKK alpha in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for IKK alpha antibody (ABIN865524)

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IKK alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3G12H9

Product Details anti-IKK alpha Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CHUK expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Alternative Name: CHUK

Background: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. Synonyms: IKK1, IKKA, IKBKA, TCF16, NFKBIKA, IKK-alpha, CHUK

Molecular Weight: 85kDa

Gene ID: 1147

Pathways: PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins