MUC1 antibody (HRP)
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- Target See all MUC1 Antibodies
- MUC1 (Mucin 1 (MUC1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MUC1 antibody is conjugated to HRP
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).
- Characteristics
- Host: Hybridization of P3X63-Ag8.653, myeloma cells with spleen cells from Balb/c mice.
- Purification
- Purified by Protein A chromatography
- Purity
- > 98 % pure
- Immunogen
- Human breast cancer cell line ZR 75-1
- Isotype
- IgG1
- Top Product
- Discover our top product MUC1 Primary Antibody
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- Application Notes
- Capture or detection antibody in serological assays for the research of antigen MUC-1. Forms a suitable pair withX108 , Catalog # L1C00802. Immunohistochemistry on frozen or paraffin sections for the detection of MUC-1. Immunochemical detection of MUC-1 protein.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1:1000~5000
- Buffer
- 150mM NaCl 10mM Tris, pH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- MUC1 (Mucin 1 (MUC1))
- Alternative Name
- CA15-3 (MUC1 Products)
- Synonyms
- CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
- Background
- Monoclonal Antibody to Carbohydrate Antigen 15-3(CA15-3) (Breast Cancer)
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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