Tamalin/GRASP antibody (AA 814-818)
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- Target See all Tamalin/GRASP (GRASP) Antibodies
- Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))
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Binding Specificity
- AA 814-818
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Reactivity
- Mouse, Rat, Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Tamalin/GRASP antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The antibody detects endogenous level of total GRASP protein.
- Purification
- Affinity purified
- Immunogen
- Peptide sequence around AA 814-818 (Q-E-I-V-R ) derived from Rat GRASP. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product GRASP Primary Antibody
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- Application Notes
- Western blotting: 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))
- Alternative Name
- GRASP (GRASP Products)
- Synonyms
- GRASP antibody, tamalin antibody, TAMALIN antibody, general receptor for phosphoinositides 1 associated scaffold protein antibody, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein antibody, GRASP antibody, grasp antibody, Grasp antibody
- Background
- GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid protein encoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipper region and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.
- Molecular Weight
- 95 kDa
- Gene ID
- 56850
- NCBI Accession
- NP_064522
- UniProt
- Q9JHZ4
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