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FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 31-35)

Details for Product anti-FLT1 Antibody No. ABIN871731, Supplier: Log in to see
Antigen
  • FLT1
  • VEGFR1
  • AI323757
  • Flt-1
  • VEGFR-1
  • sFlt1
  • FLT
  • FLT-1
  • flt1b
  • fms-related tyrosine kinase 1
  • vascular endothelial growth factor receptor 1
  • FMS-like tyrosine kinase 1
  • FMS-related tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • vascular endothelial growth factor receptor-1
  • FLT1
  • CpipJ_CPIJ012087
  • Flt1
  • flt1
  • FLT-1
Alternatives
anti-Human FLT1 antibody for Enzyme Immunoassay
Epitope
AA 31-35
51
24
18
16
15
14
14
11
9
8
5
5
5
5
5
5
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
378
123
81
16
13
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
206
201
31
7
4
1
Clonality
Polyclonal
Conjugate
This FLT1 antibody is un-conjugated
25
13
10
10
9
9
8
7
7
7
7
6
6
6
6
5
4
3
3
3
3
2
2
1
1
1
1
1
1
Application
Western Blotting (WB)
286
226
96
62
57
56
56
42
15
13
12
6
5
5
3
2
2
2
1
1
1
1
1
1
1
Options
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Immunogen Peptide sequence around AA 31-35 (D-P-E-L-S) derived from Human VEGFR1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Specificity The antibody detects endogenous level of total VEGFR1 protein.
Purification Affinity purified
Alternative Name VEGFR1 (FLT1 Antibody Abstract)
Background Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Molecular Weight 180 kDa
Gene ID 2321
NCBI Accession NP_002010
UniProt P17948
Pathways RTK Signaling
Application Notes Western blotting: 1:500-1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Rikova, Guo, Zeng, Possemato, Yu, Haack, Nardone, Lee, Reeves, Li, Hu, Tan, Stokes, Sullivan, Mitchell, Wetzel, Macneill, Ren, Yuan, Bakalarski, Villen, Kornhauser, Smith, Li, Zhou, Gygi, Gu et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).