TLR1 antibody (N-Term)

Catalog No. ABIN920636

Product Details anti-TLR1 Antibody

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Positive Control: Mouse Spleen Tissue Lysate

Purification: Antigen Immunoaffinity purified

Immunogen: Rabbit polyclonal TLR1 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TLR1.

Isotype: IgG

Application Details

Application Notes: Western blot: use at 1-2 µg/mL. Immunohistochemistry: use at 10 µg/mL

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.02% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Abstract: TLR1 Products

Synonyms: CD281 antibody, TIL antibody, TIL. LPRS5 antibody, rsc786 antibody, toll like receptor 1 antibody, toll-like receptor 1 antibody, TLR1 antibody, Tlr1 antibody

Background: Toll-like receptors (TRLs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins. Synonyms:

Molecular Weight: 90 kDa

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades