Cyclin D3 antibody (C-Term)
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- Target See all Cyclin D3 (CCND3) Antibodies
- Cyclin D3 (CCND3)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Pig, Chicken
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cyclin D3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Pig (Porcine), Chicken
- Purification
- Purified
- Immunogen
- CCND3 antibody was raised in rabbit using the C terminal of CCND3 as the immunogen
- Top Product
- Discover our top product CCND3 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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CCND3 Blocking Peptide, catalog no. 33R-1779, is also available for use as a blocking control in assays to test for specificity of this CCND3 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- Cyclin D3 (CCND3)
- Alternative Name
- CCND3 (CCND3 Products)
- Synonyms
- zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
- Background
- CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Synonyms: Polyclonal CCND3 antibody, Anti-CCND3 antibody, cyclin D3 antibody.
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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