EPH Receptor B6 antibody

Catalog No. ABIN3209999

The Mouse Monoclonal anti-EPH Receptor B6 antibody is suitable to detect EPH Receptor B6 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for EPH Receptor B6 antibody (ABIN3209999)

Target: EPH Receptor B6 (EPHB6)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8E7H12

Product Details anti-EPH Receptor B6 Antibody

Purification: Purified antibody.

Immunogen: EPHB6 antibody was raised in Mouse using a purified recombinant fragment of EPHB6 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified antibody supplied in PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Alternative Name: EPHB6

Background: EPHB6 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EPHB6 is expressed both in a variety of embryonic and adult tissues. EPHB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EPHB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition. Synonyms: Monoclonal EPHB6 antibody, Anti-EPHB6 antibody, EPH receptor B6 antibody.

Pathways: RTK Signaling, Hormone Transport