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HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Heavy Chain) antibody

Details for Product No. ABIN94366, Supplier: Log in to see
Antigen
  • MHC-G
  • B-F
  • B-F-S04
  • B-F-S05
  • B-F-S06
  • B-F-S07
  • B-FI
  • B-FIV
  • BF2
  • BFa2
  • BFw-03
  • BFw-05
  • BFz-01
  • major histocompatibility complex, class I, G
  • MHC BF1 class I
  • HLA-G
  • BF1
Epitope
Heavy Chain
73
17
8
7
7
7
7
7
6
5
4
2
2
2
1
1
1
1
1
Reactivity
Human
508
8
7
4
1
Host
Mouse
411
73
26
6
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
52
50
36
28
12
9
9
9
9
9
9
9
9
9
9
8
8
8
7
5
1
1
1
1
1
Application
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
295
284
277
155
138
131
130
109
75
22
21
8
7
3
3
2
1
1
1
1
Options
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Immunogen Denatured bacterially expressed recombinant human HLA-G heavy chain.
Clone MEM-G-1
Isotype IgG1
Specificity The antibody MEM-G/1 reacts with denaturated HLA-G heavy chain. HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells.
Purification Purified from ascites by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Alternative Name HLAG (HLAG Antibody Abstract)
Research Area Major Histocompatibility Complex (MHC)
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Immunohistochemistry (IHC) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Heavy Chain) antibody (ABIN94366) Immunohistochemistry staining with anti-human HLA-G (MEM-G/1). Fig. 1A - pulmonary di...
Immunohistochemistry (IHC) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Heavy Chain) antibody (ABIN94366) Immunohistochemistry staining with anti-human HLA-G (MEM-G/1). Fig. 1A - pulmonary di...
Product cited in: Jasinski-Bergner, Stehle, Gonschorek, Kalich, Schulz, Huettelmaier, Braun, Seliger: "Identification of 14-3-3? Gene as a Novel miR-152 Target Using a Proteome-based Approach." in: The Journal of biological chemistry, Vol. 289, Issue 45, pp. 31121-35, 2014 (PubMed).

Amiot, Vu, Rauch, LHelgoualch, Chalmel, Gascan, Turlin, Guyader, Samson: "Expression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis." in: Journal of hepatology, Vol. 60, Issue 2, pp. 245-52, 2014 (PubMed).

Larsen, Bzorek, Pass, Larsen, Nielsen, Svendsen, Lindhard, Hviid: "Human leukocyte antigen-G in the male reproductive system and in seminal plasma." in: Molecular human reproduction, Vol. 17, Issue 12, pp. 727-38, 2011 (PubMed). Further details: incubated over night at room temperature, with primary antibody MEM- G1 in a concentration of 10 ?g/ml, diluted in wash buffer

Biondi, Ferretti, Lunghi, Medici, Cervellati, Pavan, Vesce, Morano, Adinolfi, Bertoni, Abelli: "cAMP efflux from human trophoblast cell lines: a role for Multidrug Resistance Protein (MRP)1 transporter." in: Molecular human reproduction, 2010 (PubMed).

Gonen-Gross, Achdout, Arnon, Gazit, Stern, Horejsí, Goldman-Wohl, Yagel, Mandelboim: "The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, 2005 (PubMed).

Shih, Kurman: "p63 expression is useful in the distinction of epithelioid trophoblastic and placental site trophoblastic tumors by profiling trophoblastic subpopulations." in: The American journal of surgical pathology, Vol. 28, Issue 9, pp. 1177-83, 2004 (PubMed).

Boyson, Erskine, Whitman, Chiu, Lau, Koopman, Valter, Angelisova, Horejsi, Strominger: "Disulfide bond-mediated dimerization of HLA-G on the cell surface." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 25, pp. 16180-5, 2002 (PubMed).

Hurks, Valter, Wilson, Hilgert, van den Elsen, Jager: "Uveal melanoma: no expression of HLA-G." in: Investigative ophthalmology & visual science, Vol. 42, Issue 13, pp. 3081-4, 2001 (PubMed).

Frumento, Franchello, Palmisano, Nicotra, Giacomini, Loke, Geraghty, Maio, Manzo, Natali, Ferrara: "Melanomas and melanoma cell lines do not express HLA-G, and the expression cannot be induced by gammaIFN treatment." in: Tissue antigens, Vol. 56, Issue 1, pp. 30-7, 2000 (PubMed).

Fournel, Huc, Aguerre-Girr, Solier, Legros, Praud-Brethenou, Moussa, Chaouat, Berrebi, Bensussan, Lenfant, Le Bouteiller: "Comparative reactivity of different HLA-G monoclonal antibodies to soluble HLA-G molecules." in: Tissue antigens, Vol. 55, Issue 6, pp. 510-8, 2000 (PubMed).