HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) antibody

Antigen: HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG)

Synonyms: MHC-G

Clonality: Monoclonal (MEM-G-2)

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN94384

Additional Information

Alternative name: HLA-G

Immunogen: Bacterially expressed recombinant HLA-G heavy chain (denatured).

Format: Purified

Isotype: IgG1

Clone: MEM-G-2

Specificity: The antibody MEM-G/2 recognizes the free heavy chain of all the HLA-G isoforms. HLA-Gbelongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed onthe surface of trophoblast cells.

Application Details

Concentration: 1 mg/ml

Purity: > 95% (by SDS-PAGE)

Purification: Purified from ascites by hydrophobic charge induction chromatography.

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Storage: Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.

Research Area: Major Histocompatibility Complex (MHC)

Restrictions: For Research Use only

Images

Immunohistochemistry of paraffin-embedded sections (kidney)

Publications

Publications: Kren, Slaby, Muckova et al.: "Expression of immune-modulatory molecules HLA-G and HLA-E by tumor cells in glioblastomas: An unexpected prognostic significance?" in: Neuropathology : official journal of the Japanese Society of Neuropathology, 2010 (PubMed).