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ATP1B2 antibody (ATPase, Na+/K+ Transporting, beta 2 Polypeptide) (AA 121-150)

Details for Product anti-ATP1B2 Antibody No. ABIN950562, Supplier: Log in to see
Antigen
  • AMOG
  • Amog
  • Atpb-2
  • ATPB2
  • ATPB2S
  • RATATPB2S
Epitope
AA 121-150, Middle Region
16
15
14
14
10
4
2
2
1
Reactivity
Human
46
5
3
Host
Rabbit
43
4
Clonality
Polyclonal
Conjugate
This ATP1B2 antibody is un-conjugated
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
42
36
17
17
3
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 121~150 amino acids from the Center region of human ATP1B2
Isotype Ig
Specificity This antibody reacts to ATP1B2.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name ATP1B2 (ATP1B2 Antibody Abstract)
Background The protein belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.Synonyms: Sodium pump ATPase subunit beta 2, Sodium/potassium-dependent ATPase subunit beta-2, Sodium/potassium-transporting ATPase subunit beta-2
Gene ID 482
NCBI Accession NP_001669
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-ATP1B2 antibody (ATPase, Na+/K+ Transporting, beta 2 Polypeptide) (AA 121-150) (ABIN950562) ATP1B2 Antibody (Center) flow cytometry analysis of K562 cells (bottom histogram) com...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ATP1B2 antibody (ATPase, Na+/K+ Transporting, beta 2 Polypeptide) (AA 121-150) (ABIN950562) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with ATP1B2 Antibo...
Western Blotting (WB) image for anti-ATP1B2 antibody (ATPase, Na+/K+ Transporting, beta 2 Polypeptide) (AA 121-150) (ABIN950562) Western blot analysis of ATP1B2 Antibody (Center) in K562 cell line lysates (35µg/lan...
Background publications Tokhtaeva, Sachs, Vagin: "Assembly with the Na,K-ATPase alpha(1) subunit is required for export of beta(1) and beta(2) subunits from the endoplasmic reticulum." in: Biochemistry, Vol. 48, Issue 48, pp. 11421-31, 2009 (PubMed).

Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Hosgood, Menashe, He et al.: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, 2009 (PubMed).