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IL1R2 antibody (Middle Region)
IL1R2
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL1R2 Antibody
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Target
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IL1R2
(Interleukin 1 Receptor, Type II (IL1R2))
Binding Specificity
All epitopes for IL1R2 antibodies
AA 273-300, Middle Region
Reactivity
All reactivities for IL1R2 antibodies
Human
Host
All hosts for IL1R2 antibodies
Rabbit
Clonality
All clonalities for IL1R2 antibodies
Polyclonal
Conjugate
All conjugates for IL1R2 antibodies
This IL1R2 antibody is un-conjugated
Application
All applications for IL1R2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes CD121b / IL1R2.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the central region (between 273-300aa) of human CD121b / IL1R2.
Isotype
Ig Fraction
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Discover our top product IL1R2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for IL1R2
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Target
IL1R2
(Interleukin 1 Receptor, Type II (IL1R2))
Alternative Name
CD121b / IL1R2 (IL1R2 Products )
Synonyms
CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
Background
The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.Synonyms: CD121 antigen-like family member B, CDw121b, IL-1R-2, IL-1R-beta, IL1RB, Interleukin-1 receptor type II
Gene ID
7850
NCBI Accession
NP_004624
Pathways
NF-kappaB Signaling
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