FZD4 antibody (Frizzled Family Receptor 4) (C-Term)

Details for Product anti-FZD4 Antibody No. ABIN951305, Supplier: Log in to see
Antigen
  • CG4626
  • DFz4
  • Dfz4
  • Dm Fz4
  • Dmel\\CG4626
  • Fz4
  • anon-WO0170980.10
  • anon-WO0170980.11
  • fz1
  • zg01
  • CD344
  • EVR1
  • FEVR
  • FZD4S
  • Fz-4
  • FzE4
  • GPCR
  • hFz4
  • frizzled4
  • fz4
  • FZ-4
  • frizzled 4
  • frizzled homolog 4
  • frizzled-4
  • frizzled family receptor 4
  • frizzled homolog 4 (Drosophila)
  • fz4
  • fzd4
  • Tsp_10376
  • FZD4
  • Fzd4
Alternatives
anti-Human FZD4 antibody for ELISA
Epitope
C-Term, AA 501-531
26
15
13
11
10
8
8
4
4
3
3
2
2
2
1
1
1
1
1
Reactivity
Human
127
77
53
8
7
7
7
6
5
5
5
4
3
2
2
1
Host
Rabbit
80
25
22
8
Clonality
Polyclonal
Conjugate
This FZD4 antibody is un-conjugated
8
6
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
73
52
25
15
13
12
11
6
2
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 501~531 amino acids from the C-terminal region of Human CD344 / FZD4 / Frizzled-4
Isotype Ig
Specificity This antibody recognizes Human and Mouse CD344 / FZD4 / Frizzled-4 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name CD344 / FZD4 / Frizzled-4 (FZD4 Antibody Abstract)
Background FZD4 may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway.Synonyms: Fz-4, FzE4, hFz4
Molecular Weight 59881 Da
Gene ID 8322
NCBI Accession NP_036325
Pathways WNT Signaling, Hormone Transport, Sensory Perception of Sound
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-FZD4 antibody (Frizzled Family Receptor 4) (C-Term) (ABIN951305) Western blot analysis of FZD4 Antibody (C-term) in 293 cell line lysates (35ug/lane)....
Western Blotting (WB) image for anti-FZD4 antibody (Frizzled Family Receptor 4) (C-Term) (ABIN951305) Western blot analysis of FZD4 Antibody (C-term) in mouse heart tissue lysates (35ug/l...
Background publications Ells, Guernsey, Wallace, Zheng, Vincer, Allen, Ingram, DaSilva, Siebert, Sheidow, Beis, Robitaille: "Severe retinopathy of prematurity associated with FZD4 mutations." in: Ophthalmic genetics, Vol. 31, Issue 1, pp. 37-43, 2010 (PubMed).

Drenser, Dailey, Vinekar, Dalal, Capone, Trese: "Clinical presentation and genetic correlation of patients with mutations affecting the FZD4 gene." in: Archives of ophthalmology, Vol. 127, Issue 12, pp. 1649-54, 2009 (PubMed).

Robitaille, Wallace, Zheng, Beis, Samuels, Hoskin-Mott, Guernsey: "Phenotypic overlap of familial exudative vitreoretinopathy (FEVR) with persistent fetal vasculature (PFV) caused by FZD4 mutations in two distinct pedigrees." in: Ophthalmic genetics, Vol. 30, Issue 1, pp. 23-30, 2009 (PubMed).

Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, 2009 (PubMed).

Tickenbrock, Hehn, Sargin, Choudhary, Bäumer, Buerger, Schulte, Müller, Berdel, Müller-Tidow, Serve: "Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4." in: International journal of oncology, Vol. 33, Issue 6, pp. 1215-21, 2008 (PubMed).