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ITGA4 antibody (PE)
ITGA4
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
R1-2
PE
Product Details anti-ITGA4 Antibody (PE)
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Target
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ITGA4
(Integrin alpha 4 (ITGA4))
Reactivity
All reactivities for ITGA4 antibodies
Mouse
Host
All hosts for ITGA4 antibodies
Rat
Clonality
All clonalities for ITGA4 antibodies
Monoclonal
Conjugate
All conjugates for ITGA4 antibodies
This ITGA4 antibody is conjugated to PE
Application
All applications for ITGA4 antibodies
Flow Cytometry (FACS)
Specificity
This CD49d Monoclonal Antibody reacts with Alpha-4 integrin (CD49d/ITGA4).
Purification
Protein G Chromatography
Immunogen
Peyers Patch HEV binding lymphoma line (TK1). Donor: Fisher Spleen. Fusion Partner: P3x63Ag8.653.
Clone
R1-2
Isotype
IgG2b
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Discover our top product ITGA4 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Target Details for ITGA4
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Target
ITGA4
(Integrin alpha 4 (ITGA4))
Alternative Name
CD49d / ITGA4 (ITGA4 Products )
Synonyms
CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
Background
CD49d helps to mediate cell-cell and cell-matrix interactions. Alpha-4 integrin combines with b1 and b7 integrin to form VLA-4 and LPAM-1 (Peyers patch homing receptor) respectively. VLA-4 is expressed on most peripheral lymphocytes, thymocytes and monocytes. LPAM-1 is found on peripheral lymphocytes, but few thymocytes. Fibronectin and VCAM-1 act as ligands for both VLA-4 and LPAM-1. LPAM-1 also binds the mucosal vascular addressin MAdCAM-1. (1)Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4
Gene ID
16401
NCBI Accession
NP_034706
UniProt
Q00651
Pathways
Integrin Complex
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