Glypican 3 antibody (C-Term)
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- Target See all Glypican 3 (GPC3) Antibodies
- Glypican 3 (GPC3)
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Binding Specificity
- AA 464-494, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Glypican 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to GPC3.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 464-494 amino acids from the C-terminal region of human GPC3
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GPC3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Glypican 3 (GPC3)
- Alternative Name
- Glypican-3 / GPC3 (GPC3 Products)
- Synonyms
- GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
- Background
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5
- Molecular Weight
- 65563 Da
- Gene ID
- 2719
- NCBI Accession
- NP_004475
- Pathways
- Glycosaminoglycan Metabolic Process
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