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MSH2 antibody (Middle Region)
MSH2
Reactivity: Human
WB, IF, FACS, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MSH2 Antibody
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Target
See all MSH2 Antibodies
MSH2
(Mismatch Repair Protein 2 (MSH2))
Binding Specificity
All epitopes for MSH2 antibodies
AA 644-673, Middle Region
Reactivity
All reactivities for MSH2 antibodies
Human
Host
All hosts for MSH2 antibodies
Rabbit
Clonality
All clonalities for MSH2 antibodies
Polyclonal
Conjugate
All conjugates for MSH2 antibodies
This MSH2 antibody is un-conjugated
Application
All applications for MSH2 antibodies
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes human MSH2.
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the central region (between 644-673aa) of human MSH2.
Isotype
Ig Fraction
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Discover our top product MSH2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MSH2
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Target
MSH2
(Mismatch Repair Protein 2 (MSH2))
Alternative Name
MSH2 (MSH2 Products )
Synonyms
COCA1 antibody, FCC1 antibody, HNPCC antibody, HNPCC1 antibody, LCFS2 antibody, AI788990 antibody, wu:fc06b02 antibody, wu:fc13e09 antibody, zgc:55333 antibody, ATMSH2 antibody, MUTS homolog 2 antibody, msh2 antibody, mutS homolog 2 antibody, mutS homolog 2 (E. coli) antibody, MUTS homolog 2 antibody, mutS homolog 2 L homeolog antibody, MutS protein homolog 2 antibody, MSH2 antibody, Msh2 antibody, msh2 antibody, msh2.L antibody
Background
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.Synonyms: DNA mismatch repair protein Msh2, MutS protein homolog 2
Molecular Weight
104743 Da
Gene ID
4436
NCBI Accession
NP_000242
Pathways
DNA Damage Repair , Production of Molecular Mediator of Immune Response
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