PCSK6 antibody (C-Term)
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- Target See all PCSK6 Antibodies
- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
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Binding Specificity
- AA 658-688, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCSK6 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human PCSK6 (C-term).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 658-688 amino acids from the C-terminal region of human PCSK6
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PCSK6 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
- Alternative Name
- PCSK6 / PACE4 (PCSK6 Products)
- Synonyms
- PACE4 antibody, PCSK6 antibody, SPC4 antibody, C86343 antibody, Pace4 antibody, Spc4 antibody, PACE4AIIa antibody, Xpace4 antibody, spc4 antibody, proprotein convertase subtilisin/kexin type 6 antibody, peptidase S8 antibody, proprotein convertase subtilisin/kexin type 6 L homeolog antibody, PCSK6 antibody, EAMY_RS27925 antibody, pcsk6 antibody, Pcsk6 antibody, pcsk6.L antibody
- Background
- The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Paired basic amino acid cleaving enzyme 4, Proprotein convertase subtilisin/kexin type 6, SPC4, Subtilisin-like proprotein convertase 4, Subtilisin/kexin-like protease PACE4
- Molecular Weight
- 106420 Da
- Gene ID
- 5046
- NCBI Accession
- NP_612197
- Pathways
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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