pi8 antibody, cap2 antibody, CAP-2 antibody, CAP2 antibody, NK10 antibody, Spi8 antibody, ovalbumin antibody, PI8 antibody, serpin family B member 8 antibody, serpin B8 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 8 antibody, Serpinb8 antibody, SERPINB8 antibody, LOC607205 antibody, serpinb8 antibody, LOC100424017 antibody
Background
Serpins are a group of proteins with similar structures that have been shown to inhibit proteases. Many serpins, like PI8 inhibit chymotrypsin - like serine proteases (serine protease inhibitors). Human proteinase inhibitor 8 (PI8) is a widely expressed 45- kDa ovalbumin type serpin. PI8 forms a complex with Furin, a ubiquitous mammalian endoproteinase in order to inhibit it. PI8 is also a potent inhibitor of bacillus subtilis, a Gram and catalase positive bacteria commonly found in soil.Synonyms: CAP-2, CAP2, Cytoplasmic antiproteinase 2, PI-8, PI8, Peptidase inhibitor 8, Serpin B8, clade B (ovalbumin) member 8, serpin peptidase inhibitor