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Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (AA 160-189), (C-Term) antibody

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Synonyms SIT1, RP11-331F9.5, SIT, SIT-R, Sit
C-Term, AA 160-189
(16), (15), (11), (7), (3), (2), (1)
(57), (20), (13), (1), (1), (1)
(39), (13), (13)
(8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(35), (34), (11), (10), (9), (5), (2), (2), (2), (1)
Pubmed 4 references available
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Quantity 0.4 mL
Shipping to United States ( )
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Immunogen KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of Human SIT1 Genename: SIT1
Isotype Ig
Specificity This antibody recognizes Human SIT1 / SIT (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name SIT1 / SIT (SIT1 Antibody Abstract)
Background Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.Synonyms: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1
Molecular Weight 21126 Da
Gene ID 27240
NCBI Accession NP_055265
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (AA 160-189), (C-Term) antibody (ABIN954810) Western blot analysis of SIT1 / SIT Antibody (C-term) in MDA-MB453 cell line lysates ...
Background publications Chapuis, Hot, Hansmannel et al.: "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. ..." in: Molecular psychiatry, Vol. 14, Issue 11, pp. 1004-16, 2009 (PubMed).

Tedoldi, Paterson, Hansmann et al.: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, 2005 (PubMed).

Tao, Wollscheid, OBrien et al.: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, 2005 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Catalog No. ABIN954810
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