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SPI1 antibody (C-Term)
SPI1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPI1 Antibody
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Target
See all SPI1 Antibodies
SPI1
(Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
Binding Specificity
All epitopes for SPI1 antibodies
AA 216-246, C-Term
Reactivity
All reactivities for SPI1 antibodies
Human
Host
All hosts for SPI1 antibodies
Rabbit
Clonality
All clonalities for SPI1 antibodies
Polyclonal
Conjugate
All conjugates for SPI1 antibodies
This SPI1 antibody is un-conjugated
Application
All applications for SPI1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes SPI1 / Transcription factor PU.1.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 216-246aa) of human SPI1 / Transcription factor PU.1
Isotype
Ig Fraction
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Discover our top product SPI1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SPI1
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Target
SPI1
(Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
Alternative Name
SPI1 / PU.1 (SPI1 Products )
Synonyms
OF antibody, PU.1 antibody, SFPI1 antibody, SPI-1 antibody, SPI-A antibody, Dis-1 antibody, Dis1 antibody, Sfpi-1 antibody, Sfpi1 antibody, Spi-1 antibody, Tcfpu1 antibody, Tfpu.1 antibody, Pu.1 antibody, cb1086 antibody, pu.1 antibody, pu1 antibody, sfpi1 antibody, si:by184l24.2 antibody, spi1 antibody, SPI1/PU.1 antibody, spi1l antibody, zgc:152991 antibody, Spi-1 proto-oncogene antibody, spleen focus forming virus (SFFV) proviral integration oncogene antibody, Spi-1 proto-oncogene b antibody, Spi-1 proto-oncogene a antibody, SPI1 antibody, Spi1 antibody, spi1b antibody, spi1a antibody
Background
The SPI1 gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: 31 kDa transforming protein, SFPI1, SPI-1 proto-oncogene, Transcription factor PU.1, spleen focus forming virus (SFFV) proviral integration oncogene spi1
Gene ID
6688
NCBI Accession
NP_001074016
Pathways
Stem Cell Maintenance
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