ABCC2 antibody (Internal Region)

Catalog No. ABIN962562

Product Details anti-ABCC2 Antibody

Target: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABCC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts with an internal epitope of cMOAT/MRP2, a 170-180 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. Does not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products.

Purification: 0.2 Micron Filter

Immunogen: Bacterial fusion protein of cMOAB/MRP2, containing the 202-amino acid COOH terminal end of the protein.

Type of Immunogen: Fusion protein

Clone: M2III-6

Isotype: IgG2a

Application Details

Application Notes: Approved: ICC (1:20 - 1:50), IHC, IHC-Fr (1:20), IHC-P (1:20), WB (1:20 - 1:50)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supernatant, 0.7 % BSA and 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for ABCC2

Target: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Alternative Name: ABCC2 / MRP2 (ABCC2 Products)

Synonyms: ABC30 antibody, CMOAT antibody, DJS antibody, MRP2 antibody, cMRP antibody, AI173996 antibody, Abc30 antibody, Cmoat antibody, Mrp2 antibody, ATP binding cassette subfamily C member 2 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 2 antibody, ABCC2 antibody, Abcc2 antibody

Background: Name/Gene ID: ABCC2
Subfamily: ATP-binding cassette - ABCC/MRP
Family: Transporter

Synonyms: ABCC2, ABC30, CMOAT1, CMOAT, DJS, Multidrug resistance protein 2, MRP2, CMRP

Gene ID: 1244

UniProt: Q92887

Pathways: Hormone Transport