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ABCC2 antibody

ABCC2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7244276
  • Target See all ABCC2 Antibodies
    ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
    Reactivity
    • 42
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 8
    Rabbit
    Clonality
    • 27
    • 17
    Polyclonal
    Conjugate
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ABCC2 antibody is un-conjugated
    Application
    • 23
    • 13
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human ABCC2
    Isotype
    IgG
    Top Product
    Discover our top product ABCC2 Primary Antibody
  • Application Notes
    IHC 1:30-150, ELISA 1:2000-10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
    Alternative Name
    ABCC2 (ABCC2 Products)
    Synonyms
    ABC30 antibody, CMOAT antibody, DJS antibody, MRP2 antibody, cMRP antibody, AI173996 antibody, Abc30 antibody, Cmoat antibody, Mrp2 antibody, ATP binding cassette subfamily C member 2 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 2 antibody, ABCC2 antibody, Abcc2 antibody
    Background
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine, therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
    NCBI Accession
    NP_000383
    UniProt
    Q92887
    Pathways
    Hormone Transport
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