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Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) antibody

Antigen

Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1)
Synonyms
BP-1, 4EBP1, 4E-BP1, PHAS-I, MGC4316, 4e-bp1, AA959816, 153432_at, 43-BP, 4E-BP, 4EBP, BcDNA.HL08053, BcDNA:HL08053, CT8705, Dm 4E-BP, Phas1, anon-WO0172774.158, d4E-BP, d4E-BP1, d4EBP, eIF4E-BP, l(2) ... show more
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
5 references available
Catalog no. ABIN965489
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name 4E-BP1
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human 4E-BP1 around the phosphorylation site of threonine 45 (S-T-TP-P-G).
Specificity 4E-BP1 (Ab-45) antibody detects endogenous levels of total 4E-BP1 protein. This antibody may crossreact with 4E-BP2 and 4E-BP3.
Synonyms BP-1, 4EBP1, 4E-BP1, PHAS-I, MGC4316, 4e-bp1, AA959816, 153432_at, 43-BP, 4E-BP, 4EBP, BcDNA.HL08053, BcDNA:HL08053, CT8705, Dm 4E-BP, Phas1, anon-WO0172774.158, d4E-BP, d4E-BP1, d4EBP, eIF4E-BP, l(2)k07736, l(2)k13517, pp20, thor, DmelCG8846, CG8846, EIF4EBP1, fc04h09, Eif4ebp1, MGC64137, wu:fc04h09

Application Details
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Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
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Product Burnett, Barrow, Cohen et al.: "RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 4, pp. 1432-7, 1998 (PubMed).

Gingras, Kennedy, OLeary et al.: "4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway." in: Genes & development, Vol. 12, Issue 4, pp. 502-13, 1998 (PubMed).

Kumar, Pandey, Sabatini et al.: "Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation." in: The EMBO journal, Vol. 19, Issue 5, pp. 1087-97, 2000 (PubMed).

Brugarolas, Lei, Hurley et al.: "Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex." in: Genes & development, Vol. 18, Issue 23, pp. 2893-904, 2004 (PubMed).

Moody, Scott, Amirghahari et al.: "Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A." in: Journal of virology, Vol. 79, Issue 9, pp. 5499-506, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1)", type "Antibodies"
Hosts Rabbit (199), Mouse (22)
Reactivities Human (204), Mouse (Murine) (105), Rat (Rattus) (105), Cow (Bovine) (39), Dog (Canine) (38), Horse (Equine) (38), Pig (Porcine) (16), Chicken (10), Rabbit (1)
Applications Western Blotting (WB) (140), ELISA (85), Immunohistochemistry (IHC) (79), Immunofluorescence (IF) (65), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (43), Immunoprecipitation (IP) (7), Flow Cytometry (FACS) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (5), Immunocytochemistry (ICC) (4), Dot Blot (Dot) (3), Immunoelectron Microscopy (IEM) (2), Gel Shift (GS) (1)
Conjugates Alexa Fluor 350 (7), Alexa Fluor 488 (7), Alexa Fluor 555 (7), Alexa Fluor 647 (7), PE,Cy5.5 (7), Biotin (6), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2)
Epitopes pThr36 (29), pThr45 (12), pSer100 (8), pSer111 (7), pSer65 (7), C-Term (6), pSer64 (6), pThr70 (5), N-Term (4), pThr46,pThr37 (4), pThr70,pSer65 (4), Internal Region (3), Thr45 (3), pThr37 (3), pThr46 (3), AA 101-118 (2), Center (2), pThr37, pThr46 (2), pThr69 (2), Ser100 (1), Ser111 (1), Thr36 (1), Thr37, Thr46 (1), Thr46 (1), Thr69 (1), pSer112 (1), pSer425 (1), pThr417 (1), pTyr376,pTyr373 (1), pTyr530 (1)