MAP3K5
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
1E3
unconjugated
Application Notes
IHC: 1:50-1:100.
Restrictions
For Research Use only
Format
Liquid
Concentration
100ug/100ul.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Zhang, Zheng, Storz, Min: "Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor." in: The Journal of biological chemistry, Vol. 280, Issue 19, pp. 19036-44, (2005) (PubMed).
Goldman, Chen, Fu: "Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation." in: The Journal of biological chemistry, Vol. 279, Issue 11, pp. 10442-9, (2004) (PubMed).
Fujii, Goldman, Park, Zhang, Chen, Fu: "Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034." in: Oncogene, Vol. 23, Issue 29, pp. 5099-104, (2004) (PubMed).
Target
ASK1 (MAP3K5)
(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))