Cyclin D3 antibody
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- Target See all Cyclin D3 (CCND3) Antibodies
- Cyclin D3 (CCND3)
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cyclin D3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CCND3 expressed in E. Coli.
- Clone
- 6H4
- Top Product
- Discover our top product CCND3 Primary Antibody
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- Application Notes
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion." in: Pathology, research and practice, Vol. 204, Issue 8, pp. 589-97, (2008) (PubMed).
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Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion." in: Pathology, research and practice, Vol. 204, Issue 8, pp. 589-97, (2008) (PubMed).
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- Target
- Cyclin D3 (CCND3)
- Alternative Name
- CCND3 (CCND3 Products)
- Synonyms
- zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
- Background
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
- Gene ID
- 896
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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