anti-FOXO3 antibody (Forkhead Box O3)

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Antigen
Synonyms FOXO3, FKHRL1, FOXO3A, zgc:92176, wu:fb50g02, wu:fi33f07, foxo3a, xfoxo3, foxO3, foxO, AF6q21, FKHRL1P2, FOXO2, 1110048B16Rik, 2010203A17Rik, C76856, Fkhr2, Foxo3a, FoxO3A, Fkhrl1, FOXO-3
Alternatives
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(301), (119), (94), (14), (9), (8), (6), (4), (3), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(216), (60), (25), (1)
Clonality
Polyclonal
Conjugate
This FOXO3 antibody is un-conjugated
(7), (7), (7), (5), (5), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(246), (154), (125), (88), (76), (25), (21), (15), (12), (5), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR1 around the phosphorylation site of serine 253.
Specificity FKHRL1 (Ab-253) antibody detects endogenous levels of total FKHR1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name FKHRL1 (FOXO3 Antibody Abstract)
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Smith, Norton, Gorospe et al.: "Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity." in: The Journal of cell biology, Vol. 169, Issue 2, pp. 331-9, 2005 (PubMed).

Essafi, Fernández de Mattos, Hassen et al.: "Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells." in: Oncogene, Vol. 24, Issue 14, pp. 2317-29, 2005 (PubMed).

Brunet, Park, Tran et al.: "Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 952-65, 2001 (PubMed).

Goode, Grauer, Gums: "Infectious vaginitis. Selecting therapy and preventing recurrence." in: Postgraduate medicine, Vol. 96, Issue 6, pp. 85-8, 91-8, 1994 (PubMed).

Background publications Brunet, Bonni, Zigmond et al.: "Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor." in: Cell, Vol. 96, Issue 6, pp. 857-68, 1999 (PubMed).

Catalog No. ABIN966151
$398.75
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