anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha)

Details for Product anti-GSK3a Antibody No. ABIN966233
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Synonyms GSK3A, CG5182, Dmel\\CG5182, GSK3a, 2700086H06Rik, xgsk3, GSK-3[a], GSK-3[b], GSK3, gsk3a
Human, Mouse (Murine), Rat (Rattus)
(265), (122), (95), (5), (3), (2), (2), (2), (2), (2)
(214), (77), (4)
This GSK3 alpha antibody is un-conjugated
(20), (11), (10), (6), (6), (6), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC)
(245), (122), (116), (43), (40), (36), (15), (10), (9), (7), (5), (2), (1)
Pubmed 7 references available
Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen This antiserum was produced against synthesized non-phosphopeptide derived from human GSK3 around the phosphorylation site of serine 21 (T-S-SP-F-A).
Specificity GSK3 (Ab-21) Antibody detects endogenous levels of total GSK3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name GSK3alpha (GSK3a Antibody Abstract)
Pathways PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Welsh, Wilson, Proud: "GSK3: a SHAGGY frog story." in: Trends in cell biology, Vol. 6, Issue 7, pp. 274-9, 2004 (PubMed).

Barry, Graham, Fry et al.: "Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?" in: FEBS letters, Vol. 553, Issue 1-2, pp. 173-8, 2003 (PubMed).

Koivisto, Alavian, Hakkinen et al.: "Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes." in: Journal of cell science, Vol. 116, Issue Pt 18, pp. 3749-60, 2003 (PubMed).

Leadbetter: "Cultivation of recalcitrant microbes: cells are alive, well and revealing their secrets in the 21st century laboratory." in: Current opinion in microbiology, Vol. 6, Issue 3, pp. 274-81, 2003 (PubMed).

Srivastava, Pandey: "Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin." in: Molecular and cellular biochemistry, Vol. 182, Issue 1-2, pp. 135-41, 1999 (PubMed).

Pandey, Anand-Srivastava, Srivastava: "Vanadyl sulfate-stimulated glycogen synthesis is associated with activation of phosphatidylinositol 3-kinase and is independent of insulin receptor tyrosine phosphorylation." in: Biochemistry, Vol. 37, Issue 19, pp. 7006-14, 1998 (PubMed).

Cross, Alessi, Cohen et al.: "Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B." in: Nature, Vol. 378, Issue 6559, pp. 785-9, 1996 (PubMed).

Catalog No. ABIN966233
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