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Glycogen Synthase Kinase 3 alpha (GSK3a) antibody

Details for Product No. ABIN966233
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Antigen
Synonyms 2700086H06Rik, GSK3A, CG5182, Dmel\\CG5182, GSK3a, GSK-3[a], GSK-3[b], GSK3, gsk3a, xgsk3
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(212), (120), (114), (39), (36), (28), (14), (6), (4), (2), (1), (1)
Host
Rabbit
(163), (67), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(14), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Immunohistochemistry (IHC)
(188), (93), (73), (41), (40), (30), (26), (13), (9), (1)
Pubmed 7 references available
Quantity 100 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days
Catalog No. ABIN966233
385.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antiserum was produced against synthesized non-phosphopeptide derived from human GSK3 around the phosphorylation site of serine 21 (T-S-SP-F-A).
Specificity GSK3 (Ab-21) Antibody detects endogenous levels of total GSK3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name GSK3alpha
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Cross, Alessi, Cohen et al.: "Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B." in: Nature, Vol. 378, Issue 6559, pp. 785-9, 1996 (PubMed).

Pandey, Anand-Srivastava, Srivastava: "Vanadyl sulfate-stimulated glycogen synthesis is associated with activation of phosphatidylinositol 3-kinase and is independent of insulin receptor tyrosine phosphorylation." in: Biochemistry, Vol. 37, Issue 19, pp. 7006-14, 1998 (PubMed).

Srivastava, Pandey: "Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin." in: Molecular and cellular biochemistry, Vol. 182, Issue 1-2, pp. 135-41, 1999 (PubMed).

Leadbetter: "Cultivation of recalcitrant microbes: cells are alive, well and revealing their secrets in the 21st century laboratory." in: Current opinion in microbiology, Vol. 6, Issue 3, pp. 274-81, 2003 (PubMed).

Koivisto, Alavian, Hakkinen et al.: "Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes." in: Journal of cell science, Vol. 116, Issue Pt 18, pp. 3749-60, 2003 (PubMed).

Barry, Graham, Fry et al.: "Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?" in: FEBS letters, Vol. 553, Issue 1-2, pp. 173-8, 2003 (PubMed).

Welsh, Wilson, Proud: "GSK3: a SHAGGY frog story." in: Trends in cell biology, Vol. 6, Issue 7, pp. 274-9, 2004 (PubMed).

Hosts (163), (67), (3)
Reactivities (212), (120), (114), (39), (36), (28), (14), (6), (4), (2), (1), (1)
Applications (188), (93), (73), (41), (40), (30), (26), (13), (9), (1)
Conjugates (14), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (64), (26), (18), (7), (5), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN966233
385.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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