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Insulin-Like Growth Factor I (IGF1) (AA 80-96) antibody

Antigen

Insulin-Like Growth Factor I (IGF1)
Synonyms Igf-1, Igf-I, C730016P09Rik, IGF1, IGFI, IGF-I, IGFIA, IGF-IB, LOC100136741, igf1, LOC100305062, IGF1A, igf1-A
Binding Site
Alternatives

AA 80-96
Clonality Polyclonal
Host
Reactivity
Alternatives

Human, Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
2 references available
Catalog no. ABIN966342
Quantity 100myg
Price 316.25 $   Plus shipping costs $45.00
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Alternative name IGF-1
Immunogen A synthetic peptide corresponding to a sequence at the middle region of human IGF-1 (80-96 aa), different from the mouse and rat sequence by one amino acid.
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Description Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.

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Application Notes WB: The detection limit for IGF-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative 0.05mg Thiomersal, 0.05mg NaN3.
Storage At -20°C for one year. After reconstitution, at 4°C for one month.
Research Area Diabetes, Metabolism, Growth Factors
Restrictions For Research Use only

Publications
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Product Höppener, de Pagter-Holthuizen, Geurts van Kessel et al.: "The human gene encoding insulin-like growth factor I is located on chromosome 12." in: Human genetics, Vol. 69, Issue 2, pp. 157-60, 1985 (PubMed).

Jansen, van Schaik, Ricker et al.: "Sequence of cDNA encoding human insulin-like growth factor I precursor." in: Nature, Vol. 306, Issue 5943, pp. 609-11, 1984 (PubMed).