p53 antibody (Tumor Protein P53)

Details for Product anti-TP53 Antibody No. ABIN966758, Supplier: Log in to see
Antigen
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Alternatives
anti-Human p53 antibody for Affinity Purification
Reactivity
Human
2264
513
420
186
127
94
85
82
34
23
20
18
17
16
15
14
6
4
4
4
4
3
3
3
2
2
1
Host
Rabbit
1284
1083
7
3
3
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
77
74
62
52
45
44
30
30
24
24
24
24
24
24
24
23
23
23
21
20
19
18
14
14
14
14
14
12
7
4
4
4
4
4
4
4
4
3
3
2
2
1
Application
Immunohistochemistry (IHC)
1796
717
715
667
601
571
403
340
279
179
54
41
32
31
18
16
15
15
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
Options
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
Specificity P53 (Ab-15) antibody detects endogenous levels of total p53 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name P53 (TP53 Antibody Abstract)
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Lin, Chao, Saito, Mazur, Murphy, Appella, Xu: "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression." in: Nature cell biology, Vol. 7, Issue 2, pp. 165-71, 2005 (PubMed).

Vega, Sevilla, Lazo: "p53 Stabilization and accumulation induced by human vaccinia-related kinase 1." in: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10366-80, 2004 (PubMed).

Li, Zhang, Sejas, Bagby, Pang: "Hypoxia-induced nucleophosmin protects cell death through inhibition of p53." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41275-9, 2004 (PubMed).

Background publications Wang, Wiltshire, Wang, Mikell, Burks, Cunningham, Van Laar, Waters, Reed, Wang: "ATM-dependent CHK2 activation induced by anticancer agent, irofulven." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39584-92, 2004 (PubMed).