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p53 antibody (Tumor Protein P53)

Details for Product anti-TP53 Antibody No. ABIN966759, Supplier: Log in to see
Antigen
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Alternatives
anti-Human p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Reactivity
Human
1760
319
269
99
34
19
13
11
11
10
10
9
5
4
4
4
3
3
3
2
2
2
1
Host
Rabbit
1234
613
7
4
3
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
59
49
34
31
23
23
15
15
14
14
14
14
14
14
13
4
4
4
4
4
4
4
4
4
4
3
1
1
Application
Immunohistochemistry (IHC)
1379
582
528
319
315
303
235
156
99
87
53
39
35
17
16
12
12
11
11
9
4
3
3
3
2
2
2
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
Specificity P53 (Ab-315) antibody detects endogenous levels of total p53 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name P53 (TP53 Antibody Abstract)
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Merrick, Zhou, Martin, Jeyarajah, Parker, Selkirk, Tomer, Borchers: "Site-specific phosphorylation of human p53 protein determined by mass spectrometry." in: Biochemistry, Vol. 40, Issue 13, pp. 4053-66, 2001

Lu, Fisher, Bailey, Levine: "The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5923-34, 1997

Lohrum, Scheidtmann: "Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes." in: Oncogene, Vol. 13, Issue 12, pp. 2527-39, 1997