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SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (AA 1-170)

Details for Product anti-SOX2 Antibody No. ABIN967071, Supplier: Log in to see
Antigen
  • Qscn6
  • Qsox
  • Sox-2
  • rSOx
  • ANOP3
  • MCOPS3
  • RGD1565646
  • SRY-box2
  • Xsox-2
  • anop3
  • mcops3
  • sox-2
  • lcc
  • ysb
  • cb236
  • wu:fb83g04
  • wu:fc14d07
  • zgc:65860
  • zgc:77389
  • SRY (sex determining region Y)-box 2
  • quiescin Q6 sulfhydryl oxidase 1
  • SRY-box containing gene 2
  • LOC100231711
  • Qsox1
  • SOX2
  • Sox2
  • sox2
Alternatives
anti-Human SOX2 antibody for Western Blotting
Epitope
AA 1-170
55
22
19
18
16
16
15
14
13
11
7
5
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
440
152
79
30
26
19
16
12
11
10
10
10
7
4
4
4
4
3
3
2
2
1
1
1
1
1
Host
Mouse
293
155
7
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX2 antibody is un-conjugated
21
19
17
16
11
11
8
7
6
6
6
6
4
4
4
4
3
3
3
2
2
1
1
1
1
Application
ELISA, Western Blotting (WB)
320
176
134
128
121
98
89
60
14
7
6
6
6
4
2
2
2
1
1
1
1
1
1
Options
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Immunogen Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.
Clone 10F10C9
Isotype IgG1
Purification Ascitic fluid
Alternative Name SOX2 (SOX2 Antibody Abstract)
Background SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Synonyms: ANOP3, MCOPS3, MGC2413
Molecular Weight 34.3kDa
Gene ID 6657
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Pathways Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Park, Zhao, West, Yabuuchi, Huo, Ince, Lerou, Lensch, Daley: "Reprogramming of human somatic cells to pluripotency with defined factors." in: Nature, Vol. 451, Issue 7175, pp. 141-6, 2008 (PubMed).

Product cited in: Baer, Eriksson, Faull, Rees, Curtis: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." in: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, 2007 (PubMed).