AXL antibody (AXL Receptor tyrosine Kinase) (AA 466-530)

Details for Product anti-AXL Antibody No. ABIN968973, Supplier: Log in to see
Antigen
  • JTK11
  • UFO
  • AI323647
  • Ark
  • Tyro7
  • Ufo
  • AXL receptor tyrosine kinase
  • Axl receptor tyrosine kinase
  • AXL
  • Axl
Alternatives
anti-Human AXL antibody for Blocking Reagent
Epitope
AA 466-530
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24
19
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2
2
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2
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2
1
1
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Reactivity
Human
248
106
64
6
2
2
1
1
1
1
Host
Mouse
174
82
33
4
1
Clonality (Clone)
Monoclonal ()
Conjugate
This AXL antibody is un-conjugated
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12
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2
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2
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2
Application
ELISA, Western Blotting (WB)
184
106
86
54
30
26
14
10
7
6
2
2
2
1
1
1
1
1
1
Options
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Immunogen Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.
Clone 1B3A2
Isotype IgG1
Purification Ascites
Alternative Name AXL (AXL Antibody Abstract)
Background AXL: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID 558
HGNC 558
Pathways RTK Signaling, Cellular Response to Molecule of Bacterial Origin
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Western Blotting (WB) image for anti-AXL antibody (AXL Receptor tyrosine Kinase) (AA 466-530) (ABIN968973) Figure 1: Western blot analysis using AXL mouse mAb against truncated Trx-AXL recombi...
Product cited in: Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Budagian, Bulanova, Orinska, Duitman, Brandt, Ludwig, Hartmann, Lemke, Saftig, Bulfone-Paus: "Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9324-39, 2005 (PubMed).